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A new study by UMRAM researchers Professor Kader Karlı Oguz and  Arzu Ceylan Has has been published in Multiple Sclerosis and Related Disorders's November issue. In this study,  the profile of cognitive impairment in clinically isolated syndrome (CIS), and the contribution of cortical inflammation, cortical and deep gray matter atrophy, and white matter lesions to cognitive decline were investigated. For  this purpose thirty patients with clinically isolated syndrome and twenty demographically- matched healthy controls underwent neuropsychologic assessment through the Rao Brief Repeatable Battery, and brain magnetic resonance imaging with double inversion recovery using a 3T scanner.

In this study, It has been found that disease duration and educational years had contributions to some of the cognitive test scores, while age affected some volumetric measures of the brain. So while analyzing the correlations between test performances and volumetric measures, our researchers has controlled these confounding factors. By doing so, the accuracy of the correlations has also been controlled. In our patients with CIS, it was shown that cognitive impairment was mainly related to cerebral white matter, cerebellar cortical and deep gray matter atrophy, but not with cortical inflammation, at least in the early stage of disease. For article please go:

 

This year we have celebrated new year early by combining it with the Aysel Sabuncu Brain Research Center 2016 Scientific Meeting. The day started with Dr. Emre Guven's excellent talk on compressed sensing. Short four talks from the researcher of our center followed an enlightening talk by Prof. Turgay Dalkara on discovering brain. Attendance exceed the capacity of our conference room. Later 38 posters were presented and dinner was served. The event lasted about 6 hours and the total attendance was over 100 people. UMRAM and Aysel Sabuncu Brain Research Center would like to thank all speakers, and poster presenters and well as guests of the event.

 

 

A new study by UMRAM researchers has been published in Nature Scientific Reports. Using a rapid motion adaptation paradigm, they investigated the dynamics of spatiotemporal correlation between ON and OFF pathways in human vision. Their results indicated distinct temporal dynamics for the spatiotemporal correlation within and across pathway mechanisms. Click here for further information and the journal article. 

Redi Poni defended his MS thesis on Aug 15, 2016. His thesis title was "A Digitally Controlled Class-E Amplifier for MRI". In the thesis, Redi showed the feasibility of using a class-E amplifier as a very efficient amplifier for transmission of RF signal.  Furthermore, he showed that these amplifiers can be controlled digitally. The top panel of the figure shows phantom images obtained using two of these amplifiers working simultaneously. The bottom panel shows the MR image obtained when only one channel is used. Redi will continue his PhD studies in France.

Salman Ul Hassan Dar defended his thesis on Aug 2, 2016. His thesis title was 'Inter-regional connectivity in the human brain during visual search'. The focus of this work was on the inter-regional functional and effective connectivity in the human brain during natural visual search tasks.  His thesis defense committee was composed of Dr. Fatoş Yarman Vural (Middle East Technical University), Dr. Emine Ülkü Sarıtaş (Bilkent University) and Dr. Tolga Çukur (Bilkent University). His thesis adviser was Dr. Tolga Çukur. Salman will continue as a PhD student with Dr. Tolga Çukur.

full-duplex architectureMaryam Salim defended her MS thesis on May 25, 2016. Her thesis title was "Full-Duplex MRI for Zero TE Imaging." Her overall aim was to adapt the new full-duplex telecommunication technology, to the field of magnetic resonance imaging. The overall aim was to acquire MRI data while exciting the spins with an RF pulse. Maryam will continue her studies in USA in the field of electromagnetics.

Zeynep Yildirim (Graduate Researcher at UMRAM) successfully defended her MS thesis titled “Changes in fMRI resting state networks due to audiovisual induced effects on visual motion perception”. Her thesis committee members were Hulusi Kafaligonul (Advisor, Bilkent University), Aaron Clarke (Bilkent University), and Nihal Apaydin (Ankara University). She has also become the first graduate of the Interdisciplinary Neuroscience Program at Bilkent University.