{"id":10866,"date":"2020-06-26T09:29:47","date_gmt":"2020-06-26T06:29:47","guid":{"rendered":"https:\/\/umram.bilkent.edu.tr\/?p=10866"},"modified":"2020-06-26T09:30:27","modified_gmt":"2020-06-26T06:30:27","slug":"10866","status":"publish","type":"post","link":"https:\/\/umram.bilkent.edu.tr\/index.php\/tr\/2020\/06\/26\/10866\/","title":{"rendered":"UMRAM’dan Yeni Bir Makale: In vivo human head MRI at 10.5T: A radiofrequency safety study and preliminary imaging results"},"content":{"rendered":"

CMRR ve UMRAM aras\u0131ndaki i\u015fbirli\u011fine dayal\u0131 bir \u00e7al\u0131\u015fma \u201c10.5T’de in vivo insan kafas\u0131 MRG: Bir radyofrekans g\u00fcvenlik \u00e7al\u0131\u015fmas\u0131 ve \u00f6n g\u00f6r\u00fcnt\u00fcleme sonu\u00e7lar\u0131\u201d ba\u015fl\u0131\u011f\u0131 ile yay\u0131mland\u0131. Bu \u00e7al\u0131\u015fmada,\u00a0 10.5T sisteminden elde edilen ilk insan beyni g\u00f6r\u00fcnt\u00fcleri g\u00f6sterilmektedir. 10.5T \u015fu anda d\u00fcnyadaki en y\u00fcksek alan g\u00fcc\u00fc olan tam v\u00fccut g\u00f6r\u00fcnt\u00fcleme sistemidir ve Minnesota \u00dcniversitesi’ndeki CMRR’de bulunmaktad\u0131r. Makalenin ilk yazar\u0131 Prof.Dr.Ergin Atalar<\/a>‘\u0131n doktora \u00f6\u011frencisi olan Alireza Sadeghi \u2010 Tarakameh<\/a>‘dir. Makalenin k\u0131demli yazar\u0131 Yi\u011fitcan Eryaman<\/a>, CMRR’de yard\u0131mc\u0131 do\u00e7ent olarak g\u00f6rev yapmaktad\u0131r ve Bilkent \u00dcniversitesi’nden doktora derecesini alm\u0131\u015ft\u0131r. Makalenin di\u011fer yazarlar\u0131 ise Lance DelaBarre, Russell L. Lagore, Angel Torrado-Carvajal, Xiaoping Wu, Andrea Grant, Gregor Adriany, Gregory J. Metzger, Pierre-Francois Van de Moortele ve CMRR’den Kamil U\u011furbil’dir.<\/p>\n

Abstract<\/strong><\/p>\n

Purpose<\/p>\n

The purpose of this study is to safely acquire the first human head images at 10.5 T.<\/p>\n

Methods<\/p>\n

In order to ensure safety of subjects, we validated the electromagnetic (EM) simulation model of our coil. We obtained quantitative agreement between simulated and experimental B1<\/sub>+<\/sup> and specific absorption rate (SAR). Using the validated coil model, we calculated radiofrequency (RF) power levels to safely image human subjects. We conducted all experiments and imaging sessions in a controlled RF safety lab and the whole-body 10.5T scanner in the Center for Magnetic Resonance Research (CMRR).<\/p>\n

Results<\/p>\n

Quantitative agreement between the simulated and experimental results was obtained including S-parameters, B1<\/sub>+<\/sup> maps, and SAR. We calculated peak 10 g average SAR using four different realistic human body models for a quadrature excitation and demonstrated that the peak 10 g SAR variation between subjects was less than 30%. We calculated safe power limits based on this set and used those limits to acquire T2- and T2*<\/sup>-weighted images of human subjects at 10.5 T.<\/p>\n

Conclusion<\/p>\n

In this study, we acquired the first in vivo human head images at 10.5 T using an eight-channel transmit\/receive (Tx\/Rx) coil. We implemented and expanded a previously proposed workflow to validate the EM simulation model of the eight-channel Tx\/Rx coil. Using the validated coil model, we calculated RF power levels to safely image human subjects.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":7,"featured_media":10863,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[445],"tags":[],"_links":{"self":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/10866"}],"collection":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/comments?post=10866"}],"version-history":[{"count":3,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/10866\/revisions"}],"predecessor-version":[{"id":10868,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/10866\/revisions\/10868"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/media\/10863"}],"wp:attachment":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/media?parent=10866"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/categories?post=10866"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/tags?post=10866"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}