{"id":12847,"date":"2026-01-13T13:42:27","date_gmt":"2026-01-13T10:42:27","guid":{"rendered":"https:\/\/umram.bilkent.edu.tr\/?p=12847"},"modified":"2026-01-13T13:42:27","modified_gmt":"2026-01-13T10:42:27","slug":"the-neurobiological-mechanisms-underlying-stress-susceptibility","status":"publish","type":"post","link":"https:\/\/umram.bilkent.edu.tr\/index.php\/2026\/01\/13\/the-neurobiological-mechanisms-underlying-stress-susceptibility\/","title":{"rendered":"The Neurobiological Mechanisms Underlying Stress Susceptibility"},"content":{"rendered":"<p style=\"font-weight: 400;\"><strong>Emine Eren Ko\u00e7ak<\/strong><\/p>\n<p style=\"font-weight: 400;\">Hacettepe University<\/p>\n<p style=\"font-weight: 400;\"><strong>Date\/Time: <\/strong>Thursday, 22 January 2026, 16:30 am<\/p>\n<p style=\"font-weight: 400;\"><strong>Place: <\/strong>Aysel Sabuncu Brain Research Center Seminar Room (SC-106)<\/p>\n<p><span lang=\"EN-GB\">\u00a0<\/span><\/p>\n<p align=\"center\"><b><span lang=\"EN-GB\">Abstract:<\/span><\/b><\/p>\n<p><span lang=\"EN-GB\">One of the most fundamental questions in psychiatry is why certain individuals develop mental disorders after exposure to stressors while others don\u2019t. This talk explores the neurobiological basis of stress susceptibility. Dendritic atrophy is well-demonstrated after chronic stress exposure in medial prefrontal cortex(mPFC), which is circuit specific: Chronic stress induces dendritic atrophy in entorhinal cortex\u2013projecting pyramidal neurons but spares basolateral amygdala (BLA)\u2013projecting pyramidal neurons. We examined whether synapses onto the mPFC exhibit similar region-specificity and whether these morphological changes are adaptive. Intriguingly, we found that layer-specific reorganization of basolateral amygdala and hippocampal inputs to the mPFC distinguishes stress-susceptible mice from stress-resilient ones.<\/span><\/p>\n<p><span lang=\"EN-GB\">\u00a0<\/span><\/p>\n<p align=\"center\"><b><span lang=\"EN-GB\">Bio:<\/span><\/b><\/p>\n<p><span lang=\"EN-GB\">Emine Eren-Ko\u00e7ak is a Professor at the Institute of Neurological Sciences and Psychiatry at Hacettepe University. She is a psychiatrist and holds a PhD degree in neuroscience. She completed her PhD dissertation thesis at the Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, USA under the supervision of Prof. Dr. Huda Akil. Her research focuses on the fundamental mechanisms underlying stress-related psychiatric disorders and neurodevelopmental disorders. She is particularly interested in the neurobiological mechanisms that render individuals susceptible to stress. She is a recipient of the Science Academy\u2019s Young Scientists Award Program (BAGEP), the Hacettepe Science Incentive Award, and the T\u00fcrkan Saylan Science Award.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Emine Eren Ko\u00e7ak Hacettepe University Date\/Time: Thursday, 22 January 2026, 16:30 am Place: Aysel Sabuncu Brain Research Center Seminar Room (SC-106) \u00a0 Abstract: One of the most fundamental questions in psychiatry is why certain individuals develop mental disorders after exposure to stressors while others don\u2019t. This talk explores the neurobiological basis of stress susceptibility. Dendritic [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":12280,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[746],"tags":[],"_links":{"self":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/12847"}],"collection":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/comments?post=12847"}],"version-history":[{"count":1,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/12847\/revisions"}],"predecessor-version":[{"id":12848,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/12847\/revisions\/12848"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/media\/12280"}],"wp:attachment":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/media?parent=12847"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/categories?post=12847"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/tags?post=12847"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}