{"id":9027,"date":"2019-12-09T17:58:59","date_gmt":"2019-12-09T14:58:59","guid":{"rendered":"https:\/\/umram.bilkent.edu.tr\/?p=9027"},"modified":"2019-12-10T11:25:52","modified_gmt":"2019-12-10T08:25:52","slug":"an-article-published-in-vivo-human-head-mri-at-10-5t-a-radiofrequency-safety-study-and-preliminary-imaging-results","status":"publish","type":"post","link":"https:\/\/umram.bilkent.edu.tr\/index.php\/2019\/12\/09\/an-article-published-in-vivo-human-head-mri-at-10-5t-a-radiofrequency-safety-study-and-preliminary-imaging-results\/","title":{"rendered":"In vivo human head MRI at 10.5T: A radiofrequency safety study and preliminary imaging results"},"content":{"rendered":"<section class=\"kc-elm kc-css-584166 kc_row\"><div class=\"kc-row-container  kc-container\"><div class=\"kc-wrap-columns\"><div class=\"kc-elm kc-css-484911 kc_col-sm-12 kc_column kc_col-sm-12\"><div class=\"kc-col-container\"><div class=\"kc-elm kc-css-243106 kc_text_block\"><div class=\"abstr\">\n<p>Our PhD student <a href=\"https:\/\/umram.bilkent.edu.tr\/index.php\/teams\/alireza-sadeghi-tarakameh\/\">Alireza Sadeghi\u2010Tarakameh<\/a>, <a href=\"https:\/\/umram.bilkent.edu.tr\/index.php\/teams\/ergin-atalar\/\">Prof. Dr. Ergin Atalar<\/a> and our PhD alumni <a href=\"https:\/\/umram.bilkent.edu.tr\/index.php\/teams\/yigitcan-eryaman\/\">Yi\u011fitcan Eryaman<\/a> published a paper titled &#8220;<em>In vivo human head MRI at 10.5T: A radiofrequency safety study and preliminary imaging results<\/em>\" with Lance DelaBarre, Russell L. Lagore, Angel Torrado\u2010Carvajal, Xiaoping Wu, Andrea Grant, Gregor Adriany, Gregory J. Metzger, Pierre-Francois Van de Moortele, and Kamil Ugurbil in Magnetic Resonance in Medicine.<\/p>\n<p>Abstract<\/p>\n<p><span style=\"font-size: 16px;\">PURPOSE:<\/span><\/p>\n<div class=\"\">\n<p>The purpose of this study is to safely acquire the first human head images at 10.5T.<\/p>\n<p>METHODS:<\/p>\n<p>To ensure safety of subjects, we validated the electromagnetic simula-tion model of our coil. We obtained quantitative agreement between simulated and experimental <span class=\"TextRun SCXW89437638 BCX0\" lang=\"TR-TR\" xml:lang=\"TR-TR\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW89437638 BCX0\">B<\/span><\/span><span class=\"TextRun SCXW89437638 BCX0\" lang=\"TR-TR\" xml:lang=\"TR-TR\" data-contrast=\"auto\"><span class=\"NormalTextRun Subscript SCXW89437638 BCX0\" data-fontsize=\"14\">1<\/span><\/span><span class=\"TextRun SCXW89437638 BCX0\" lang=\"TR-TR\" xml:lang=\"TR-TR\" data-contrast=\"auto\"><span class=\"NormalTextRun Superscript SCXW89437638 BCX0\" data-fontsize=\"14\">+<\/span><\/span>\u00a0and specific absorption rate (SAR). Using the validated coil model, we calculated radiofrequency power levels to safely image human subjects. We con-ducted all experiments and imaging sessions in a controlled radiofrequency safety lab and the whole-body 10.5T scanner in the Center for Magnetic Resonance Research<\/p>\n<p>RESULTS:<\/p>\n<p>Quantitative agreement between the simulated and experimental results was obtained including S-parameters, B+1 maps, and SAR. We calculated peak 10 g average SAR using 4 different realistic human body models for a quadrature excita-tion and demonstrated that the peak 10 g SAR variation between subjects was less than 30%. We calculated safe power limits based on this set and used those limits to acquire T2- and T\u22172-weighted images of human subjects at 10.5T.<\/p>\n<p>CONCLUSIONS:<\/p>\n<p>In this study, we acquired the first in vivo human head images at 10.5T using an 8-channel transmit\/receive coil. We implemented and expanded a previously proposed workflow to validate the electromagnetic simulation model of the 8-channel transmit\/receive coil. Using the validated coil model, we calculated radiofrequency power levels to safely image human subjects.<\/p>\n<p><span class=\"sourceTitle\">MAGNETIC RESONANCE IN MEDICINE<\/span><\/p>\n<p class=\"FR_field\"><span class=\"FR_label\">DOI:<\/span>\u00a010.1002\/mrm.28093<\/p>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":9033,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[256],"tags":[],"_links":{"self":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/9027"}],"collection":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/comments?post=9027"}],"version-history":[{"count":14,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/9027\/revisions"}],"predecessor-version":[{"id":9085,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/posts\/9027\/revisions\/9085"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/media\/9033"}],"wp:attachment":[{"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/media?parent=9027"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/categories?post=9027"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/umram.bilkent.edu.tr\/index.php\/wp-json\/wp\/v2\/tags?post=9027"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}