A new study by Dr. Oktay Algın has been published. In this study, visibility and patency of Liliequist’s membrane are investigated on 3D-SPACE images. As a result, 3D-SPACE sequence (with variant FA mode) is proven to be a feasible method of demonstration of this important membrane.

Feasibility of 3D-SPACE technique on the assessment of CSF related structures was first shown by Dr. Algın 7 years ago on preliminary animal experiments. Studies about applications of 3D-SPACE technique on various fields have been done since then in UMRAM. Please find more details in the link below:

We have celebrated the coming year of 2016 in UMRAM traditionally. We would like to thank everybody who came celebrate it with us. We wish all our members and alike to have a wonderful, successful year.


ASELSAN and Bilkent University UMRAM have partnered in a colloborative project that aims to significantly reduce MRI scan times to improve patient comfort and monitoring efficiency while reducing healthcare costs. For more information:

ASELSAN Research Center and Bilkent University have established a collaboration to develop clinically feasible applications of Compressive Sensing Magnetic Resonance Imaging (CS-MRI), which has been accelerated by the recent agreement between ASELSAN and Bilkent University – National Magnetic Resonance Research Center (UMRAM). The project aims to reduce the scan-times nearly 5-fold for major clinical MRI applications, enabling wider clinical use of Compressive Sensing techniques. Accelerating MRI scans potentially improves patient comfort and imaging resolution, while reducing scan costs. 

A new study from Prof. Dr. Kader Karlı Oğuz ve Arzu Ceylan HAS has been published in Archives of Gerontology and Geriatrics. In the present study, the CSF Aβ1–42, t-tau, and p-tau181 levels as well-known biomarkers of Alzheimer Disease (AD) pathology as well as the CSF α-synuclein levels as another marker of synaptic and/or neuronal injury in a group of newly diagnosed patients with AD in comparison with the controls were analyzed. Default mode network (DMN) activity and cognitive profiles of the same subjects were also comparatively examined in relation to these biomarkers. As a novel finding, in DMN, decreased connectivity of the dorsal posterior cingulate cortex with the retrosplenial cortex was found to be closely related to decreased CSF Aβ1–42 levels in patients with AD.

Please see the following link for the full article:




Prof. Dr. Kader Karli Oguz and Arzu Ceylan HAS have a new publication that investigate the effects of smoking on regional brain volumes and lesion load in patients with clinically isolated syndrome by using quantitative magnetic resonance imaging. The study included age, sex and pack year matched 31 patients and 27 healthy controls, categorized in 4 groups as smoker patients and controls, nonsmoker patients and controls. Smoking duration was significantly negatively correlated with intracranial volume and left hemisphere cortical gray matter volume. Clinically Isolated Syndome related regional brain atrophy might vary in extent and severity with smoking. Despite increased lesion load, less cortical and deep gray matter damage with a possible neuroprotective effect occurs in smoking. Please see the following link for the full article:

A new study from Prof. Dr. Kader Karlı Oğuz ve Arzu Ceylan HAS has been published in International Journal of Neuroscience. Here, the differences in the white matter structure in the patients with Chronic relapsing inflammatory optic neuropathy (CRION) were studied. Fractional anisotropy, mean diffusivity, radial and axial diffusivity values were calculated in the identified region of interests. At the same time the average difference maps were obtained by TBSS in the patients with CRION. Please see the following link for the full article: